Search on: VOLTAGE-DEPENDENT ANION CHANNELS 
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Descriptor English:   Voltage-Dependent Anion Channels 
Descriptor Spanish:   Canales Aniónicos Dependientes del Voltaje 
Descriptor Portuguese:   Canais de Ânion Dependentes de Voltagem 
Tree Number:   D12.776.157.530.400.500.520
D12.776.543.550.425.730.520
D12.776.543.585.400.730.520
Definition English:   A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role in mitochondrial CELL MEMBRANE PERMEABILITY, are often regulated by BCL-2 PROTO-ONCOGENE PROTEINS, and have been implicated in APOPTOSIS. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2006(1985) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   50859 
Unique Identifier:   D050994 

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